Theses from 2023
1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Adult Zebrafish as a Model for Parkinson’s Disease, Emmeline Bagwell
Tandem Peptides Targeting HER2 for Delivery of CD44 siRNA into HER2+ Breast Cancer Cells in Vitro, James Kalogeros
Multiplex Gene Editing in Hepatocytes as a Therapeutic Approach for Familial Hypercholesterolemia, Sarah Minich
Effects of IVD-Like Pressure and pH on Human Adipose Derived Mesenchymal Stem Cells, Alexandria Pendino
Medical Simulation-Based Sensor Methods for Ultrasound-Guided Dialysis Cannulation Skill Assessment, Devansh Shukla
An In Vivo Biocompatibility Analysis of A Novel Tissue Regeneration Matrix Using A Pig Model, Shamar Thomas
Photodynamic Therapy to Treat Triple Negative Breast Cancer in Vitro, Hunter S. Warren
Theses from 2022
Design of a Four Channel Pulsatile Perfusion Bioreactor for ex-Vivo Study of Vascular Grafts, Thomas M. Fair
Fabrication of Hydrogel Microparticles for Acute Treatment of Penetrating Brain Injuries, Isabell Foulger
Tissue-Engineered Living Pulmonary Valve for Young Adult Patients, Erica Hoskins
A 3D Tissue Engineering Model to Study Mitral Valve Annulus Calcification under Diabetic Conditions, Erin James
Nonlinear Optical Microscopy Assessment of Tissue Structure and Chondrocyte Viability of Articular Cartilage, Michael Le
Portable U-Bent Optical Fiber Biosensor for Detecting Microcystin-LR, Quan Dio Anh Le
Optimizing CRISPR/Cas9-mediated knockdown of ANGPTL3 in liver cell lines and mouse hepatocytes, Meredith Reeves
Theses from 2021
Site-specific Nanoparticle Therapy for Treatment of Medial Arterial Calcification, Tyler James Gibson
Bovine Intervertebral Disc Organ Culture for Assessing Regenerative Therapeutics for Herniation Repair, Mario Josef Krussig
Diagnosis of Myocardial Hypertrophic Disease States Through Machine Learning and Mechanistic Modeling, Michael William Ward
Theses from 2020
Design and Development of an Unconstrained Spine Test Rig to Study the Kinematics of Spine Motion, Nisha Gulhane
Effect of Aging Time on Stiffness in Acid Catalyzed Silica Sol-Gels, Satya Kalidindi
Mechanical Analysis of Double Network Hydrogels to Determine Suitability as an Articular Cartilage Substitute, Casey Virginia Young
Theses from 2019
Lectin Coated Electrodes For Biosensor Water Testing Applications, Aniqa Nuzhat Chowdhury
An Ex Vivo Model of Elastin Degradation in Porcine Carotid Arteries for the Study of Abdominal Aortic Aneurysms, Hannah Gore
Investigating Low Culture Temperature and Low Media pH of Two Chinese Hamster Ovary (CHO) Cell Lines with Next Generation RNA Sequencing (RNA-Seq) Technology, Timothy James Lindquist
Differential Gene Expression in Tendinopathy: Insights into the Failure of Wound Healing, Michael Maggio
A Multimodal Exploration of Altered Mechanical and Histological Properties in Tendons with Degenerative Tendinopathy, Olivia Newkirk
Reprocessing Protocol Validation for Medical Devices Used in Low-Resource Settings, Sarah Zemitis
Theses from 2018
System for the Application of Hydrostatic Pressure and Mechanical Strain to Cell Cultures, Justin Bacaoat
A Computational Model of the Pulmonary Fibroblast Signaling Network as Related to Idiopathic Pulmonary Fibrosis, Jessica Lennox Batista
Effect of Total Knee Replacement Conformity on Articular Constraint in Mechanical Testing, Madeline Bebler
Comparing the Therapeutic Efficacy of Human Amniotic Membrane and Adipose-Derived Mesenchymal Stem Cells in Mitigation of Osteoarthritis, Mackenzie Catherine Bowman
Stretching Vascular Smooth Muscle Cells on Micropatterned Surfaces, Suzanne Nicole Bradley
Vascular Tissue Engineering in Metabolic Syndrome Conditions – in vitro Studies, Anna Lu Carter
Regeneration of the Ventricular Endocardium Within Acellular Whole Rabbit Hearts Using a Layer-by-Layer Seeding Method, Clayton Lewis Compton
Quantitative Histological Analysis of Fixation Points on Explanted Hernia Mesh, Brittney Cotton
Self-Assembling Peptide Hydrogel for Local Anticancer Prodrug Delivery in the Treatment of Glioblastoma Multiforme, Arica Gregory
Liposomal Combination Drug and siRNA Delivery to Combat Drug-Resistant Ovarian Cancer, Emily Margaret Miller
Combinatorial Therapy of Doxorubicin and MDR1 SiRNA by Polymeric Micellar Nanoparticles in Treatment of Multidrug Resistance in Breast Cancer, David Lamar Oglesby
Histological Evaluation of the Effects of Diabetes on Renal Vasculature, David Pollard
The Detrimental Effects of Cigarette Smoke on Fracture Healing in a Bilateral Femur Fracture Rodent Model, Russell Abbott Reeves
Mechanical Characterization of the Mesh-Tissue Composite Using Abdominal Wall Tissue Phantoms and Experimental Simulations, Mathew Murphy Stanford
A Sensor Based Approach to Analyzing Motion in Medical Applications: AV Fistula Cannulation and Rett Syndrome, Jared J. Wells
Theses from 2017
Fabrication and Characterization of Electrospun Anti-Proliferative Sutures for Vascular Applications, Erica Beal
The Effect of Hydrostatic Pressure on Neuronal Cell Morphology In Vitro, Kallie Etten
Evaluating Stem Cell Response to a Spider Silk Scaffold, Katherine Lee Hafner
Novel device for improved diagnosis and monitoring of rotator cuff injury, Brittany Nicole Hall
Improving Cell Seeding of Decellularized and Porated Porcine Arterial Scaffolds, Harrison Smallwood
The Effect of Surface Roughness Modifications and Chitosan Surface Coatings on Biofilm Formation for Prevention of Orthopaedic Infections, Nathan Dewayne Smith
Formulating a composite scaffold with tissue regeneration and anti-cancer activity, Kendyl Marie Williams
Theses from 2016
Controlling Thermal Gelation Properties of Novel Tetronic® Hydrogel-Based Tissue Adhesive, Martin Fernando Alejos
Glenoid Baseplate Micromotion in Reverse Total Shoulder Arthroplasty, Jennifer Kristin Anderson
Cell Source Optimization for Cardiac Tissue Engineering, Joshua Biggs
Endothelialization of the Coronary Vasculature in Decellularized Heart Scaffolds, Jessica Lan Canavan
Proof of Concept for a Urine-Based Method for Monitoring Blood Phenylalanine for Patients with PKU, Alexandra Cholewczynski
Development of Low-Cost Impedimetric Biosensors for Clinical Diagnostics and Water Testing, Andrew Lehron Cobb
Fabrication and Characterization of an Extracellular Matrix Hydrogel for Aortic Valve Applications, Brady Culbreth
Fabrication and Characterization of Heparin-Immobilized Electrospun Nanofibers for Vascular Suture Applications, Michael J. DiBalsi
Characterization of Particulate in Vacuum Casting for Long Term Space Flight, Devin Elizabeth Gibson
In Vitro Studies of Heparin-Coated Magnetic Nanoparticles for Potential Use in the Treatment of Neointimal Hyperplasia, Andrew Hargett
Development and Initial Validation of a Surgical Instrument for In Situ Mechanical Characterization of Surgical Mesh-tissue Composites, Jorge Ivan Hernandez Sanchez
Design and Manufacture of a Biodegradable Ureteral Stent, James Hyde
Tannic Acid Crosslinked Collagen Type I for Prevention of Local HER2-Positive Breast Cancer Recurrence, Lauren Gayle Jordan
Cellular Interactions Underlying Vascular Calcification in Diabetes, Lisa Ann Larrew
Development of a Tissue-Mimicking Brain Phantom for Neurosurgical Pre-Operative Planning and Training, Miriam Navarro Lozoya
The Development of a Biomimetic Patch for Annulus Fibrosus Repair, Rachel Michelle McGuire
Simulating Burial Settings: Laboratory-Scale Forensic Bioreactor, VeeAnder Sheldonia Mealing
Immunomodulatory Effects of Human Adipose Derived Stem Cells on Human Macrophages in Diabetic Environment, Maria Margarita Portilla
An Investigation Into The Effects Of Low-Dose Gamma Radiation On Porcine Digital Flexor Tendons, Megan Keira Robson
The Cellular and Molecular Characterization of Essential Hypertension Using Innovative Pathology Models, Joshua T. Rodriguez
Autologous Protein Solution Exhibits Potential to Mitigate Osteoarthritis (OA) Progression in a Human Explant Co-Culture Model, Kathleen Emily Steckbeck
Design and Initial Verification of a Novel Total Knee Replacement that Incorporates Synthetic Ligaments to Influence Knee Stability, Michael David Stokes
Fabrication and Characterization of a Novel Porous Polymer Microsphere - Hydrogel Composite for Cell Therapy, Prathik Thulluri
Proof of Concept Studies for Point of Care Rotator Cuff Tissue Engineering, Alison Welch
Endothelialization and In Vitro Characterization of a Small Diameter Tissue Engineered Vascular Graft for Patients with Diabetes, Eric Brandon Wright
Theses from 2015
Characterization of a Multi-Laminate Angle-Ply AF Patch for Annulus Fibrosus Repair, Ryan Borem
PHYSICAL CHARACTERIZATION OF SURGICAL MESH AFTER FUNCTION IN HERNIA REPAIR, Erin McClure Casey
Influence of low shear and cyclic strain on hyperglycemic rat aortic smooth muscle cells: An In Vitro dynamic disease model, Varun Chawla
DECELLULARIZED BOVINE NUCLEUS PULPOSUS AS A BIOMIMETIC SCAFFOLD FOR INTERVERTEBRAL DISC REGENERATION, Christopher Fernandez
Endothelialization Using Protein Substrates and Hydrogels for Aortic Valve Applications, Elizabeth A. Fontaine
Bioprinting as a Tool to Evaluate Interactions of Cancerous and Noncancerous Cells, Holly Jordan
Micro and Molecular Phase Modulation for Long-Lasting Absorbable, Compliant Polymers for Orthopedic Applications, John Aaron Lilley
Analyzing User Acceptance of Mobile Technology in Clinical Settings through Point-of-Care Mobile Applications, Leanne Elizabeth Loper
Magnetic Nanoparticles in the Prevention of Neointimal Hyperplasia, Elliott Mappus
PRIMARY FLEXION AXIS SELECTION IN TOTAL KNEE REPLACEMENTS USING COMPUTATIONAL ANALYSIS, Nicholas Marais
Evaluation of Isokinetic Single-Leg Cycling as a Rehabilitation Exercise Following Anterior Cruciate Ligament Reconstruction Surgery, Jessica Myers
Analysis of Citrate Content in Bone Using High Performance Liquid Chromatography, Matthew Konstantin Pysh
Assessment of Bore-Cone Taper Junctions in Explanted Modular Total Hip Replacements, Christine Margaret Stamer
Theses from 2014
Deveopment of Explant Registry and Mechanical Testing of Pristine and Explained Surgical Mesh, Colin Burns-Heffner
Development of poly(lactic acid)-poly(ethylene glycol) nanoparticles for the delivery of non- toxic drug in combination therapy for the treatment of glioblastoma and neuroblastoma, Olivia Grace DeCroes
Development of poly(lactic acid)-poly(ethylene glycol) nanoparticles for the delivery of non- toxic drug in combination therapy for the treatment of glioblastoma and neuroblastoma, Olivia Grace DeCroes
The Delivery of Poly(lactic acid) Poly(ethylene glycol) Nanoparticles Loaded with Non-Toxic Drug to Overcome Drug Resistance for the Treatment of Neuroblastoma, Jhilmil Dhulekar
AN ENGINEERING APPROACH TO FORENSIC METHODS: THE CITRATE METHOD FOR POSTMORTEM INTERVAL DETERMINATION, Melissa Dunphy