patent number 7914819
Disclosed are a series of kneadable, pliable polymers for use in forming compositions that can be used as bone wax or as a cellular scaffold. Polymers can include a polysaccharide backbone and can be biocompatible and thrombogenic. In addition, the compositions can be osteoconductive as well as biodegradable. The disclosed compositions can be used to help control bleeding from bone surfaces as well as to promote bone regeneration and fusion. The compositions can inhibit the growth of microorganisms in implantation sites and can be loaded with additional bioactive agents to further promote healing and infection prevention.
Clemson University Research Foundation (Anderson, SC, US)