Title

Ratiometric Single-Nanoparticle Oxygen Sensors for Biological Imaging

Authors

Changfeng Wu, Clemson University
Barbara Bull, Clemson University
Kenneth Christensen, Clemson UniversityFollow
Jason McNeill, Clemson University

Document Type

Article

Publication Date

2-2009

Publication Title

Angewandte Chemie International Edition

Publisher

WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Abstract

It makes sense: Conjugated polymer nanoparticles doped with a platinum porphyrin dye exhibit bright phosphorescence that is highly sensitive to the concentration of molecular oxygen. The small size, extraordinary brightness, excellent sensitivity, and ratiometric emission, together with the demonstration of single-particle sensing and cellular uptake, indicate the potential of the nanoparticle sensors for quantitative mapping of local molecular oxygen concentration.

Comments

This manuscript has been published in the journal Angewandte Chemie International Edition.

Please find the published version here (note that a subscription is necessary to access this version):

http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291521-3773

Wiley holds the copyright in this article.

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Please use publisher's recommended citation.