Document Type

Article

Publication Date

4-4-2020

Publication Title

Journal of Cardiovascular Translational Research

Publisher

Springer Nature

DOI

10.1007/s12265-020-09993-4

Abstract

We developed models of pulmonary artery (PA) size in Fontan patients as a function of age and body surface area (BSA) using linear regression and breakpoint analyses based on data from 43 Fontan patients divided into two groups: the extracardiac conduit (ECC) group (n = 24) and the non-ECC group (n = 19). Model predictions were compared against those of a non-Fontan control group (n = 18) and published literature. We observed strong positive correlations of the mean PA diameter with BSA (r = 0.9, p < 0.05) and age (r = 0.88, p < 0.05) in the ECC group. The absolute percentage differences between our BSA and age model predictions against published literature were less than 16% and 20%, respectively. Predicted PA size for Fontan patients was consistently smaller than the control group. These models may serve as useful references for clinicians and be utilized to construct 3D anatomic models that correspond to patient body size or age.

Comments

This manuscript has been published in the Journal of Cardiovascular Translational Research. Please find the published version here (note that a subscription is necessary to access this version):

https://link.springer.com/article/10.1007%2Fs12265-020-09993-4#citeas

2020_PA_Size_supplement.pdf (617 kB)
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Available for download on Sunday, April 04, 2021

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