Document Type

Article

Publication Date

3-2017

Publication Title

IET Nanobiotechnology

Volume

11

Issue

2

Publisher

The Institution of Engineering and Technology

Abstract

The focus of this review is to assess the current status of three-dimensional (3D) carbon-electrode dielectrophoresis (carbonDEP) and identify the challenges currently preventing it from its use in high-throughput applications such as sample preparation for diagnostics. The use of 3D electrodes over more traditional planar ones is emphasised here as a way to increase the throughput of DEP devices. Glass-like carbon electrodes are derived through the carbonisation of photoresist structures made using photolithography. These biocompatible carbon electrodes are not ideal electrical conductors but are more electrochemically stable than noble metals such as gold and platinum. They are also significantly less expensive than common electrode materials, both in terms of material cost and fabrication process. CarbonDEP has been demonstrated for the manipulation of microorganisms and biomolecules. This review is divided in three main sections: (i) carbonDEP fabrication process; (ii) applications using 3D carbonDEP; and (iii) challenges and perspectives on the use of carbonDEP for high-throughput applications.

Comments

This manuscript has been published in the journal IET Nanobiotechnology. Please find the published version here (note that a subscription is necessary to access this version):

http://digital-library.theiet.org/content/journals/10.1049/iet-nbt.2016.0154

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