The Effect of Magnetically Induced Colloidal Arrangements on the Biomedical Applications of Magnetite
Dr. Thompson Mefford
Materials Science and Engineering
The design, functionalization, characterization, and applications of magnetic nanoparticles have garnered significant interest over the past several decades. However, even though using magnetic nanoparticles to accomplish these goals has been the subject of intense study; the fundamental properties of these systems remain poorly understood. Specifically, it is not well known how the formation of clusters and linear aggregates affects the properties of these materials and their applications. It has been recently reported that for some suspensions of magnetic nanoparticles the application dependent properties of the sample is a function of the time exposed to a magnetic field. This time dependence has been linked to the formation of linear aggregates or chains in an applied magnetic field. In this work we examine the relationships between colloidal stability, the formation of these linear structures, and changes observed in the proton transverse relaxation rate and heating rate in magnetic hyperthermia of aqueous suspensions of magnetic particles. Our results indicate that varying the ligand length has a direct effect on the colloidal arrangement of the system in a magnetic field, producing differences in the rate and size of chain formation, and hence systematic changes in transverse relaxation and heating rates.
Saville, Steven; Stone, Roland; Qi, Ben; Woodward, Robert; House, Mike; St. Pierre, Tim; and Meffo, O. Thompson, "The Effect of Magnetically Induced Colloidal Arrangements on the Biomedical Applications of Magnetite" (2013). Graduate Research and Discovery Symposium (GRADS). 75.