Theses from 2023
Investigating the Potential of a Cell-Based Gene Editing Therapy for Inherited Metabolic Liver Disease, Ilayda Ates
In Vitro and in Vivo Diabetic Models for Assessment of Tissue Engineered Vascular Grafts, Juan Carlos Carrillo Garcia
Assesment of Structure, Function, and Microevolutionary Dynamics of Extrachromosomal Circular DNA in Chinese Hamster Ovary Cells, Dylan Chitwood
Advancement of Detection and Treatment for Triple-Negative Breast Cancer and Infectious Disease, Austin Smothers
3D Printing with Photopolymerizable Polyester Resins for Resorbable Medical Device Applications, Mathew Murphy Stanford
Development & Validation of Needle-based Metrics for Hemodialysis Cannulation Skill Assessment, Ziyang Zhang
Prevention and Reversal of Elastin-Associated and Phosphate-Dependent Arterial Calcification Using Targeted Nanotherapeutics in Pre-clinical Models, Fatema Tuj Zohora
Theses from 2022
The Development and Analysis of Methods Used to Evaluate American Football Facemasks, Alexander Bina
Highly Adherent Antimicrobial Coatings for Orthopedic Implants, Mikhail Bredikhin
In Vitro Bioreactor for Mechanical Control and Characterization of Tissue Constructs, Samuel Coeyman
Development of a Tissue Engineered Cardiac Patch, Howard Herbert
Multi-Scale Vertebral-Kinematics Based Simulation Pipeline of the Human Spine With Application to Spine Tissues Analysis, Mohd Jaradat
Understanding Vascular Pathologies in Diabetes: Optimizing Tissue Engineered Blood Vessels Resistant to Diabetic Complications, Bethany Lefeber
Scalable Data-Driven Predictive Modeling and Analytics for CHO Process Development Optimization, Sarah Mbiki
Mitral Valve Tissue Engineering - A Dynamic Model for Investigating the Mechanism of Valvular Pathology, Collin Owens
Investigating Spatial Heterogeneity In Myocardial Wound Environments To Improve Therapy, Michael Potter
Nonviral Approaches for Delivery of CRISPR-Cas9 Into Hepatocytes for Treatment of Inherited Metabolic Disease, Tanner R. Rathbone
Development and Application of 3D Kinematic Methodologies for Biomechanical Modelling in Adaptive Sports and Rehabilitation, Anne Marie Severyn
Using in vitro, in silico, and in-Classroom Techniques to Address the Gender Data Gap in Health Care, Kelsey Watts
Systems Modeling of Collagenous Tissue Degradation: Protease and Mechanical Interactions, Amirreza Yeganegi
Theses from 2021
Development of a Tissue Engineered Pulmonary Heart Valve for Pediatric Patients, Maria Margarita Rodriguez Bruce
Development of a Hybrid Hydrogel Drug Delivery System for Treatment of Ischemic Injury, Andrew DeMaria
Influencing the Inflammatory Response Through Multi-Scale Geometry, Antibiotic Release, and Fluid Management in a Textile-Based Biomaterial Wound Dressing, Elizabeth Gianino
Development of Solution Blow Spun Nanofibers as Electrical and Whole Cell Biosensing Interfaces, Craig Levar Miller
Systems Modeling to Predict Mechano-Chemo Interactions In Cardiac Fibrosis, Jesse Daniel Rogers
Novel Peptide Biomaterials for Enhanced Delivery of siRNA Cargo for Treatment of Ovarian Cancer, Timothy Samec
Development of Tissue Engineered Scaffolds for Cardiovascular Repair and Replacement in Pediatric Patients, Dipasha Sinha
The Fundamentals of Fretting Crevice Corrosion of Metallic Biomaterials for Orthopedic Implants, Dongkai Zhu
Theses from 2020
Using Heparin-Coated Nanoparticles in the Treatment of Neointimal Hyperplasia, Nardine M. Ghobrial
Experimental Characterization and Biological Assessments of Polymeric Mesh Implants, Xinyue Lu
Understanding Corrosion in Modular Acetabular Tapers: Retrieval Analysis, In Vitro Testing and Cell-Material Interactions, Aarti Shenoy
Development of Extracellular Vesicle Isolation and Model Systems Toward Early Ovarian Cancer Diagnostics, Tyler Slonecki
Compliance, Hardness, and Fretting Corrosion in Modular Taper Junctions: The Micromechanics of Contact, Stephanie Marie Smith
Diagnosis, Rupture Risk Evaluation and Therapeutic Intervention of Abdominal Aortic Aneurysms Using Targeted Nanoparticles, Xiaoying Wang
Theses from 2019
The Mechanical and Functional Effects of Ionizing Radiation on Articular Cartilage, Hannah Cash
The Role of Tbx5 in Sinoatrial Node Differentiation in Mouse Embryonic Stem Cell Derived Cardiomyocytes, Yunkai Dai
Development of Tissue Engineered Vascular Grafts Resistant to Diabetes Mellitus, Jhilmil Dhulekar
Targeted EDTA Chelation Therapy with Albumin Nanoparticles to Reverse Arterial Calcification and Restore Vascular Health in Chronic Kidney Disease, Saketh Ram Karamched
Electrochemical Assessment of Alumina-TiC Composite: A Potential Biomaterial, Hetal Umesh Maharaja
Understanding the Warburg Phenotype and the Metabolic Plasticity of Proliferative Mammalian Cells Using 13C Metabolic Flux Analysis, Daniel Odenwelder
Development of a Nucleus Pulposus Implant for Intervertebral Disc Repair, Joshua Dillon Walters
Inflammation and Corrosion in Total Hip Prostheses: The Generation and Interaction of Reactive Oxygen Species with CoCrMo Metallic Biomaterial Surfaces, Michael John Wiegand
Polarization-Resolved Second Harmonic Generation Microscopy Study of Cardiac Hypertrophy, Cai Yuan
Theses from 2018
Development of a Biomimetic, Collagen-Based Scaffold for the Repair and Regeneration of the Annulus Fibrosus, Ryan Borem
Engineering Soft Tissue Replacements and the Development of Novel Technologies to Heal these Wounds, Sarah Grace Dennis
Chemically Active Rheological Modifiers for the Improved Clinical Use of Cyanoacrylates, Kyle Joseph Garcia
Computational Approaches to Understanding Structure-Function Relationships at the Intersection of Cellular Organization, Mechanics, and Electrophysiology, Tyler George Harvey
Simulated Inflammation by Hypochlorous Acid and the Corrosion and Tribocorrosion of Orthopedic Alloys: Feedback Between Corrosion and Inflammation, Gregory Walter Kubacki
Tissue Engineering Platforms for Cardiac Pathology in Diabetes: In Vitro and In Vivo Studies, Laura Elizabeth McCallum
Targeted Delivery of Drug Loaded Albumin Nanoparticles to Emphysematous Lungs to Preserve Elastin and Mitigate Matrix Metalloproteinase Activity, Vaideesh Parasaram
Development of Biomimetic Models of Human Cardiac Tissue, Dylan Jack Richards
Computational Modeling of Nonlinear Behavior in Orthopaedics, Kyle Snethen
Behavioral, Functional, and Shape Assessment for Temporomandibular Joint, Feng Wei
Theses from 2017
Antifibrotic Effects of Vibratory Stimulation, Sooneon Bae
Whole Body Irradiation and Degradation of Structural and Functional Properties of Mouse Bone: X-rays, Protons, and Heavy Ions, Laura Christine Bowman
In Vitro Diabetic-Hypertensive Cellular-Response Evaluation Model for In-Stent Restenosis, Varun Chawla
Development of a Tissue Engineered Mitral Valve, Christopher Patrick deBorde
Naturally Derived Anti-Inflammatory and Antibacterial Coatings for Surgical Implants, Dmitry Gil
Target-Specific Capture of Relevant Gaseous Compounds Using Natural and Synthetic Nano and Micro Materials, Fernanda Delbuque Guerra
Flow Assessment Using Optical Coherence Microscopy Based Particle Image Velocimetry, Siyu Ma
Towards Computer Aided Management of Kidney Disease, Vipul Pai Raikar
Towards Real-time Remote Processing of Laparoscopic Video, Zahra Ronaghi
Nanowired Human Cardiac Spheroids for Cardiac Regenerative Medicine, Yu Tan
Multifunctional Polymeric Micelles for Drug Resistant Breast Cancer: Self-Assembling Poly(Lactide-Co-Glycolide)-Graft-Polyethylenimine, Graham MacKenzie Temples
Real-time Observation of Dynamic Sarcomeric Addition in an In Vivo-like Cardiomyocyte Culture Model, Zhonghai Wang
Theses from 2016
Computational Studies of Molecular Mechanisms Mediating Protein Adsorption on Material Surfaces, Tigran M. Abramyan
Nutrient Related Mechanisms of Intervertebral Disc Degeneration, Sarah Elizabeth Cisewski
Creation of a Pioneer-Neuron Axonal Pathfinding Model for Future Applications in Developmental Neurotoxicity Testing, Nicholas Robert Erdman
Understanding the Transcriptional Landscape of Chinese Hamster Ovary (CHO) Cell Lines Using Next-Generation Sequencing Technology, RNA-seq, under Industrially Relevant Conditions, Yogender Kumar Gowtham
Targeted Nano-Therapeutices for the Reversal of Calcification and ECM Degradation in Abdominal Aortic Aneurysms, Nasim Nosoudi
Impact of Ionizing Radiation Dose and Dose Rate on Adipose Stem Cell Function, Matthew Connor Rusin
Comprehensive Investigation into the Utility of Amnion Membrane Derived Stem Cells for Orthopedic Regenerative Medicine Applications, Natasha Topoluk
Theses from 2015
Manipulation of the Electrical Double Layer for Control and Sensing in a Solid State Nanopore, Samuel L. Bearden
Investigating into the Dynamics of Mammalian Cell Growth: Using In Vitro to Help Improve Therapies, Arthur Nathan Brodsky
Design and Development of a Selectively Absorbable Multiphasic Hernia Mesh an In Vivo Performance as it Relates to Biocompatibility, Georgios T. Hilas
Trilayer Tissue Engineered Heart Valves for Aortic Valve Replacement, Michael Paul Jaeggli
Carbon Nanotube-Enzyme Conjugates for the Fabrication of Diagnostic Biosensors, Olukayode Adedamola Karunwi
Hybrid Hydrogels for Tissue Engineering, Ho Joon Lee
Understanding the Fusion and Maturation of Tissue Engineered Linear Blood Vessels Using Magnetic Cellular Spheroids, Timothy R. Olsen
Development and Validation of a Novel In Vitro Model for the Assessment of Heterocellular Interactions Mediated by Connexin43, Emily Ongstad
Mechanically- and Electrochemically- Induced Damage at Metal Interfaces of Joint Replacements and the Biological Consequences, Pooja Panigrahi
CONTRA-COMPARTMENTAL JOINT MECHANICS IN UNICONDYLAR KNEE ARTHROPLASTY, Roy Rusly
CAPILLARY CHANNEL POLYMER FIBER-BASED SCAFFOLDS FOR NEURAL REGENERATION, Atanu Sen
Investigating Polymer based Scaffolds for Urinary Bladder Tissue Engineering, Srikanth Sivaraman
Development and Fabrication of Novel Woven Meshes as Bone Graft Substitutes for Critical Sized Defects, Jordan Anthony Stowe Gilmore
DEVELOPMENT, VALIDATION, AND APPLICATION OF ANALYTICAL METHODS FOR CHARACTERIZING ADSORBED PROTEIN ORIENTATION, CONFORMATION, AND BIOACTIVITY, Aby Thyparambil
Biomechanical Characterization and Modeling of Human TMJ Disc, Gregory Wright
Theses from 2014
Investigating the Effects of Biochemical and Biophysical Signals on Vascular Smooth Muscle Cell Differentiation, Ruikai Chen
Cardiovascular Tissue Engineered Constructs for Patients With Diabetes, James Chow
MONTE CARLO MODELING BASED PATIENT DOSE OPTIMIZATION IN DIAGNOSTIC RADIOLOGY, Wenjun He