Document Type
Patent
Publication Date
12-13-1994
Patent Number
patent number 5372818
Abstract
A novel method for using domperidone, a dopamine receptor antagonist, for treating fescue toxicosis in animals is provided. Fescue toxicosis is caused by animals grazing on endophyte-infected fescue grass. Treatment of the animal with various dosages of domperidone results in effective management of the toxin. The domperidone treatments do not cause any substantial adverse behavioral or neurological side effects in the animal. Domperidone is a more effective treatment for fescue toxicosis than previously-known agents such a metoclopramide and sulpiride.
Application Number
08/012296
Assignees
Clemson University (Clemson, SC)
Filing Date
1993-02-01
Primary/U.S. Class
424/442
Other/U.S. Class
514/276, 514/450
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