Supporting data for: Gene-rich UV sex chromosomes harbor conserved regulators of sexual development (Carey et al., 2021)
Non-recombining sex chromosomes, like the mammalian Y, often lose genes and accumulate transposable elements, a process termed degeneration. The correlation between suppressed recombination and degeneration is clear in animal XY systems, but the absence of recombination is confounded with other asymmetries between the X and Y. In contrast, UV sex chromosomes, like those found in bryophytes, experience symmetrical population genetic conditions. Here we generate and use nearly gapless female and male chromosome-scale reference genomes of the moss Ceratodon purpureus to test for degeneration in the bryophyte UV sex chromosome system. We show the moss sex chromosomes evolved over 300 million years ago and expanded via two chromosomal fusions. Although the sex chromosomes show signs of weaker purifying selection than autosomes, we find suppressed recombination alone is insufficient to drive gene loss on sex-specific chromosomes. Instead, the U and V sex chromosomes harbor thousands of broadly-expressed genes, including numerous key regulators of sexual development across land plants.
Saski, Christopher; Shu, Shenqiang; Conrad, Roth; Tiley, George; McBreen, Jordan; Shenqiang, Avinash; McDaniel, Stuart; Fernandez-Pozo, Noe; Wickett, Norman; Landis, Jacob; Schmutz, Jeremy; Daum, Chris; Burleigh, Gordon; Payton, Adam; Lovell, John; Kollar, Leslie; Johnson, Matthew; Barry, Kerrie; Healey, Adam; Maumus, Florian; Chen, Cindy; Grimwood, Jane; Jenkins, Jerry; Olsson, Sanna; Huttunen, Sanna; Rensing, Stefan; Carey, Sarah; Lipzen, Anna; Wang, Mei (2021), "Supporting data for: Gene-rich UV sex chromosomes harbor conserved regulators of sexual development (Carey et al., 2021)", Zenodo, doi: 10.5061/dryad.v41ns1rsm